Adaku C. Ume, Tara-Yesomi Wenegieme, and Clintoria R. Williams Recently, research has directed its interests into identifying molecular pathways implicated in calcineurin inhibitor (CNI)-induced renal fibrosis. An emerging body of studies investigating calcineurin (CnA) activity has identified distinct actions of two main ubiquitously expressed isoforms: CnAα and CnAβ. CNIs have the capacity to inhibit both […]
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NADPH oxidase-2 mediates zinc deficiency-induced oxidative stress and kidney damage. Mirandy S. Li, Sherry E. Adesina, Carl L. Ellis, Jennifer L. Gooch, Robert S. Hoover and Clintoria R. Williams Zn2+ deficiency (ZnD) is comorbid with chronic kidney disease and worsens kidney complications. Oxidative stress is implicated in the detrimental effects of ZnD. However, the sources […]
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Zinc Deficiency Induces Hypertension by Promoting Renal Na+ Reabsorption Clintoria R. Williams, Monisha Mistry, Aswathy M. Cheriyan, Jasmine M. Williams, Meagan K. Naraine, Carla L. Ellis, Rickta Mallick, Abinash C. Mistry, Jennifer L. Gooch, Benjamin Ko, Hui Cai and Robert S. Hoover Zn2+ deficiency (ZnD) is a common comorbidity of many chronic diseases. In these […]
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