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Kidney Pathophysiology Research Group

Zinc Supplementation: A Possible Offramp from the Road to End Stage Kidney Failure

  • March 1, 2023
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Ume, Adaku C.; Wenegieme, Tara-Yesomi; Adesina, Sherry E.; Williams, Clintoria R. Globally, over 103 million individuals are afflicted by CKD, a silent killer claiming the lives of 1.2 million people annually. CKD is characterized by five progressive stages, in which dialysis and kidney transplant are life-saving routes for patients with end stage kidney failure. While kidney damage impairs kidney function […]

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Zinc Deficiency Promotes Kidney Damage

  • April 4, 2020
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NADPH oxidase-2 mediates zinc deficiency-induced oxidative stress and kidney damage. Mirandy S. Li, Sherry E. Adesina, Carl L. Ellis, Jennifer L. Gooch, Robert S. Hoover and Clintoria R. Williams Zn2+ deficiency (ZnD) is comorbid with chronic kidney disease and worsens kidney complications. Oxidative stress is implicated in the detrimental effects of ZnD. However, the sources […]

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Zinc Deficiency Plays a Role in High Blood Pressure

  • January 23, 2019
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Zinc Deficiency Induces Hypertension by Promoting Renal Na+ Reabsorption Clintoria R. Williams, Monisha Mistry, Aswathy M. Cheriyan, Jasmine M. Williams, Meagan K. Naraine, Carla L. Ellis, Rickta Mallick, Abinash C. Mistry, Jennifer L. Gooch, Benjamin Ko, Hui Cai and Robert S. Hoover Zn2+ deficiency (ZnD) is a common comorbidity of many chronic diseases. In these […]

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